Antibiotic Utilization in Acute Pancreatitis: A Narrative Review

Acute pancreatitis is a complex inflammatory disease with significant morbidity and mortality. Despite advances in its management, the role of antibiotics prophylaxis treatment acute remains controversial. The aim this comprehensive review to analyze current evidence on use pancreatitis, focusing prophylactic therapeutic strategies. Prophylactic aims prevent local systemic infections. However, recent studies have questioned routine for highlighted potential risks antibiotic resistance adverse effects. In selected high-risk cases, such as infected necrotizing therapy may still be beneficial. As use, are usually used treat pancreatic necrosis extrapancreatic When selecting an antibiotic, microbiologic profile patterns should considered. Combination broad-spectrum often recommended cover both Gram-positive Gram-negative pathogens. Recent research has importance individualized approaches underscored need tailored approach based patient-specific factors. This also highlights new antimicrobial agents alternative strategies, probiotics, management pancreatitis.